In this study, cross reactivity between Toxocara vitulorum (T. vitulorum) and Toxocara canis (T. canis) was evaluated. Twelve rabbits were divided into 4 equal groups; the first was infected with embryonated             T. vitulorum eggs (10000 embryonated eggs for each rabbit); the second was infected with the same dose of T. canis, the third was immunized with T. vitulorum antigen and challenged with T. canis and the fourth group given Freund's adjuvant as a control negative group. All these groups were tested by ELISA for detection of serum antibodies. Furthermore, Western Blot was applied to determine the common epitopes between the two species of Toxocara. ELISA results revealed that, the mean positive antibody titres recovered from the third group were (0.984), (0.958), (0.982) and (0.954) at the days 14, 21, 30 and 45 p.i respectively. Moreover, immunoblotting revealed that protein bands of molecular weights 43, 40, 33, and 18 kDa respectively at the days 30 and 45 p.i, were common between Toxocara vitulorum and Toxocara canis. From these bands, prospective vaccine production against toxocariasis could be done.