A total of two hundred and fifty random samples of infants milk formulae (IMF) for babies after birth (70 samples), milk-based cereal weaning food and dried milk powder (90 samples each) were purchased from different shops and pharmacies in Assiut city and villages around the city. These samples were transferred to the laboratory in their packages to be examined microbiologically to evaluate their quality. The average values of aerobic plate count (APC), psychrotrophic, B. cereus and total yeasts and molds counts were 9.2x10, 6.1x10 and 1.3x10²; 2.9x10²,2.9x10³ and 2.8x10²; 0.3x10, 0.56x10 and 7.2x10 and 3.0x10, 8.0x10 and 5.1x10 cfu/g of examined samples, respectively. Moreover, B. cereus, enterococci and anaerobes could be isolated in various percentages from the examined samples. Furthermore, Ent. cloaca, Serratia marcescens and Klebsiella oxytoca were isolated from IMF in percentages of 42.9, 42.9 and 14.2%, respectively. Concerning milk-based cereal baby food, Ent. cloaca, Ent. sakazakii; Serratia marcescens; Serratia liquefaciens; Ent. aerogenes; K. oxytoca; Citrobacter freundii; Hafnia alvei; Proteus spp.; Salmonella spp < /em>. and Chryseomonas luteola were found in 13, 6, 1, 2, 1, 4, 1, 5, 5, 1, 1 and 1 of tested samples, respectively. While, Ent. cloaca; Ent. sakazakii; Serratia marcescens; Hafnia alvei; Y. pestis and Y. pseudotuberculosis were existed in dried milk powder samples in  incidences of 42.9, 7.1, 7.1, 21.4, 14.3 and 7.1 %, respectively. Recommendations were suggested to safeguard the existence of such microorganisms in infants' milk food and to avoid their undesirable changes resulted in economic losses as well as public health hazards.