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172832

RELATIONSHIP BETWEEN OXIDATIVE AND CYTOGENETIC STATUS OF DAIRY COWS AND RECURRENT SUBCLINICAL MASTITIS CAUSED BY STAPHYLOCOCCUS AUREUS

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Last updated: 05 Jan 2025

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Abstract

Dairy cattle are susceptible to a variety of metabolic and infectious diseases. Mastitis is one of the most important diseases in dairy production sector causing losses in milk production. Concerning the subclinical mastitis (SCM), the main form of mastitis in modern herds, Staphylococcus aureus (S.aureus) is the most frequent and major pathogen causing it. So, the current work was conducted to determine the possible relationship between the recurrent SCM caused by S.aureus and the changes that occur in the oxidant / antioxidant parameters and the cytogenetic picture of cows using these changes as predictive biomarkers. Ten healthy and 21 recurrent SCM cows infected with S.aureus were selected after bacteriological examination. Milk and 2 blood samples were taken from each cow. Milk sample was used for California Mastitis Test (CMT), Somatic Cell Count (SCC) and bacteriological examination. First blood sample was used for plasma separation and estimation of malondialdehyde (MDA), Nitric Oxide (NO), Total Antioxidant Capacity (TAC), glutathione peroxidase (GSH-Px) and catalase (CAT). The second whole blood sample was used for cytogenetic examination. Results of SCM cows revealed imbalance between the oxidant (MDA and NO) and antioxidant (TAC, GSH-PX and CAT activities) parameters. Additionally, cytogenetic changes were represented by increasing the percentage of gaps, deletions and total aberrated cells. In conclusion, the recurrent SCM cows affected with S.aureus were undergoing the stress of lactation, infection and inflammation that consequently alter the oxidative status and cytogenetic picture of affected cows.

DOI

10.21608/avmj.2012.172832

Authors

First Name

EBTIHAL

Last Name

A. IBRAHIM

MiddleName

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Affiliation

Department of Biology of Reproduction, Animal Reproduction Research Institute, Alharm- Giza, Egypt.

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Orcid

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First Name

MAHA

Last Name

A. IBRAHIM

MiddleName

-

Affiliation

Department of Biology of Reproduction, Animal Reproduction Research Institute, Alharm- Giza, Egypt

Email

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City

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Orcid

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First Name

EBTSAM E.Z.

Last Name

KOTB

MiddleName

-

Affiliation

Department of Mastitis and Neonatal Diseases, Animal Reproduction Research Institute, Alharm- Giza, Egypt.

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Volume

58

Article Issue

133

Related Issue

24335

Issue Date

2012-04-01

Receive Date

2012-03-24

Publish Date

2012-04-01

Page Start

1

Page End

11

Print ISSN

1012-5973

Online ISSN

2314-5226

Link

https://avmj.journals.ekb.eg/article_172832.html

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https://avmj.journals.ekb.eg/service?article_code=172832

Order

24

Type

Research article

Type Code

1,840

Publication Type

Journal

Publication Title

Assiut Veterinary Medical Journal

Publication Link

https://avmj.journals.ekb.eg/

MainTitle

RELATIONSHIP BETWEEN OXIDATIVE AND CYTOGENETIC STATUS OF DAIRY COWS AND RECURRENT SUBCLINICAL MASTITIS CAUSED BY STAPHYLOCOCCUS AUREUS

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Article

Created At

23 Jan 2023