The aim of this study was to assess the pathological effects of different doses of Low-Level Laser Therapy (LLLT) on the healing of full-thickness skin wounds in goats. Full-thickness skin wounds were surgically created on the lateral aspect of the thigh of 24 Nubian goats. Those goats were divided randomly into four equal groups according to the time of scanning with continuous waves of He-Ne laser. Scanning with 0.00J/cm², 0.640J/cm², 1.28J/cm² and 2.00J/cm² was applied for 0, 200, 400 and 600 seconds daily for twenty one days to group Ι, II, III and IV respectively. LLLT treated wounds showed contraction and regression in size, enhanced reepithilization and acceleration in maturation phase. LLLT irradiation affects relief of pain positively. Each LLLT dose was found to affect the above parameters of wound healing differently but in conclusion the lower dose (0.640J/cm²) was found to be the most suitable dose to be used in wound healing in goatskin