A total of ninety seven broiler chicks in Sulaimania/ Kurdistan region/ Republic of Iraq, were collected from different flocks at different dates suffering from nephritis. Samples of affected kidneys were cultured on blood, Mannitol salt and MacConkey agar plates, the isolates were confirmed by API 20E system. The isolated microorganism included E.coli (89.69%), Proteus milabilis (9.27%) and Klebsiella pneumonia (1.03%). Antimicrobial susceptibility test for E.coli showed high sensitivity to Ciprofloxacin and Co-trimoxazole. Histopathological changes of the kidneys were characterized by enlargement of epithelial cells of renal tubules and pale cytoplasm, engorgement of blood capillaries in both renal glomeruli and interstitial tissues with atrophy of renal glomeruli