One hundred fifty seven samples from one humped camel (Camelus dromedarius) were collected in three different areas (Draw, Gharb Aswan Village and Gharb Sohil Village) in Aswan Governorates from April 2014 to April 2015, eleven camels suffered from blood parasite Trypanosoma evansi, thirty one camels suffered from internal parasites Tricuries Cameli, ninety nine camels suffered from clinical mange infestation, free from internal and blood parasites and sixteen clinically healthy camel. Infected animals with mange were significant decreases in TEC, Hb, Basophil and Monocytes, while significant increases in TLC, Eosinophils, Lymphocytes and Neutrophil. There was a significant increased in Triglyceride and glucose concentrations in infected male than healthy, while it show a significant decreased in infected female than healthy, in addition to Albumin, ALT, HDL and Calcium levels had no significant different between infected and healthy, but AST, LDL and cholesterol levels show a significant increased in infected animals than healthy.