Artemisia herba alba and Allium sativum grow in Sinai peninsula and, Northern area of Egyptian Delta respectively. Both extracts plants were evaluated as anti–insect products in an effort to develop alternative insecticides considering the environment. The effect of Artemisia and Allium extracts on some Biological aspects as well as some digestive enzymes changes after treatment with those extracts have been studied. The results indicated that treatment the 3rd instar larvae of Spodoptera littoralis for 24hours revealed satisfactory effect in larval mortality (50%) and significant prolongation for both larval and pupal durations. This prolongation was accompanied with a decrease in the percentage of pupation and adult emergence. Digestive enzymatic activities were pronounced on estimation of Trehalase, Invertase and Amylase manifested obvious changes in the treated larvae of Spodoptera littoralis.