This study was carried on 747 sheep located in Dakahlia Governorate, Delta region, Egypt, over one year (March 2014 to February 2015). Out of them 43 sheep showed different nervous signs. The diseased sheep were incised and examined for the presence of Coenurus cerebralis cysts to study the clinical, risk factors, and some epidemiological pattern of coenurosis. Brain samples from 43 diseased sheep from four localities in Dakahlia Governorate were collected. The various nervous clinical signs of coenurosis were presented in variant degrees regarding to the affected site and location of the coenurus cyst. The clinical manifestation represented by head tilting 42%, head pressing 3.48%, dropping of ears 49%, circling 70%, blindness 16%, recumbencey 30%, and posterior paralysis 11.53%. The relationship between the site of coenurus cyst and the manifested clinical signs could help in predicting the location of the cyst from the clinical signs for further interference specially in case of  valuable animals. A significant correlation was detected between prevalence of coenurosis, rearing system, availability of dogs & fox and locality at P-values < (0.019, 0.019 and 0.044, respectively).The risk factors and epidemiological patterns could help in developing control measures.