Minerals play an important role in improving reproductive efficiency in all animals. It is very important for animal production and reproduction. Deficiency of minerals may lead to disorders affecting growth, production and reproductive health of animals. Different trace elements (selenium, cobalt, iodine, iron, zinc, copper and manganese) can influence reproductive performance of animals. Reproductive failure may be occared by deficiencies of one or mor trace minerals and by imbalances. A total number of 230 cows from New Valley governorate (Kharga, Dakhla and Paris) were used in this study. About 35 hybrids cattle were suffered from silent heat, inactive ovaries and post parturient reproductive troubles. Animals were clinically and gynecologically examined, blood samples were collected for carrying out some related analyses. Results explained that 22 of the examined animals showed clear clinical signs of copper deficiency (hypocupremia) and had a poor body condition, score and anemia, Also, 13 of these hypocupremic cows had a mixed selenium, cobalt and iodine deficiency and suffered from ovarian inactivity in comparison with control cows.