A total of 168 samples of livers, kidneys and muscles (part of the diaphragm) of both buffalo and cattle were screened in the period from October 2007 to September 2008. The samples were subjected to preparation & for measurement the level of zinc by using Atomic Absorption/Flaming Emission Spectrophotometer. Buffalo organs showed variations in their zinc content. Concentrations of zinc in buffalo livers were 11.89 ± 2.03 as a mean with a range varied from 8.0 to 16.0 µg/g wet weight. While the concentration of zinc in kidneys of buffalo varied from 11.00 to 22.00 with a mean value of 14.06 ± 3.24 µg/g wet weight, respectively. Moreover, the concentrations of zinc in muscles were 18.07 ± 6.39, 12.21 and 35.0 µg/g wet weight, respectively as a mean, minimum and maximum. On the other hand, concentrations of zinc in cattle livers, the levels varied from 8.78 to 40.0 with a mean value of 13.19 ± 6.40 µg/g wet weight. While in kidneys the concentrations were 10.23, 30.0 and 14.60 ± 4.30 µg/g wet weight, respectively as a minimum, maximum and mean. Moreover, the mean zinc concentrations in cattle muscles was 17.25 ± 5.77 with a range of 11.43 – 35.00 µg/g wet weight. In conclusion, 3% - 28% of the examined samples of both cattle and buffalo were higher than the results obtained by Egyptian Organization Standardization and Quality Control (2008), muscles samples have high concentrations of zinc than livers and kidneys. However, it is still not toxic to human because zinc daily requirement is about 15 mg/day which is never found in the daily serving of meat group of food.