Abstract This research aims to study the effect of organizational Ambidexterity on job performance, from the point of view of managers and their deputies in the small and medium industrial companies, in the industrial zone of New Damietta. A special survey questionnaire has been designed for this purpose and distributed to the study sample, which was a sample quota. The number of companies under study reached (512) companies, and the sample size was (384) individuals, the questionnaire was distributed to them. The good ones were for statistical analysis (198) questionnaires. The results showed a significant correlation between search variables, and that there is a significant effect of a dimension of organizational Ambidexterity on the dimensions of job performance, which is dimension exploitation at a significant level of 0.01, While dimension exploration had no significant effect on the dimensions of functionality, From the point of view of managers and their deputies in the companies under study. And the value (R²) was 0.27, 0.28, and 0.21 in the dimensions of job performance (task performance, contextual performance, and Creative performance) respectively