Purpose: To demonstrate the visual and refractive outcomes of wavefront -guided laser in situ
keratomileusis 6 m postoperatively for low to moderate myopia in Assiut, Egypt. Methods: This
prospective study took into account 39 eyes of 23 subjects treated with wavefront-guided LASIK
who were available for evaluation at 6 months. All participants were subject to preoperative
wavefront analysis, which was performed with a Hartmann-Shack aberrometer, VISX WaveScan
system. The clinical outcomes of wavefront-guided LASIK were evaluated in terms of in terms of
safety, efficacy, predictability, stability, complications, and preoperative and postoperative aberrations. Results: Following the 6 month benchmark 13 eyes had no change in best spectaclecorrected visual acuity and 25 gained 1 or more lines. Only one eye lost one line. The safety
index was 1.15 and the efficacy index, 1.06. 94.9 % of the eyes were within ± 0.50 diopter of
emmetropia. Uncorrected visual acuity was 20/20 or better in 28 of the eyes. Supernormal vision
(Best corrected visual acuity of 20/10 or better) was achieved in 32 of the eyes. There was a
significant increase in Root mean Square, coma and spherical aberrations 6m. postoperatively.
Trefoil aberration was significantly decreased. No complications have been observed, such as
epithelial ingrowth, diffuse lamellar keratitis, or infection was observed and Trefoil was decreased.
Conclusion: Wavefront-guided LASIK provides significant improvement of Best corrected visual
acuity, and significant increase in Root mean Square and coma while trefoil was significantly
decreased.