Purpose: To compare visual quality (UCVA, BCVA, and contrast sensitivity) and optical quality (High
order aberrations) of Femtosecond assisted LASIK and implantable collamer lens implantation
in correction of high myopia. Methods: This study was non-randomized comparative prospective
consecutive interventional study. It included 31 eyes with high myopia (≥ -6 Ds) of 21 patients
attended to the outpatient ophthalmic clinic of Sohag university hospitals from the period from
Jan.2016 to Jan.2017. The patients were divided into two groups depending on: Degree of myopia,
corneal thickness and corneal tomography. Group A (14 eyes) of 12 patients were subjected to
implantable collamer lenses implantation and Group B (17 eyes) of 9 patients were subjected to
femtosecond assisted LASIK. Results: Postoperative data in both groups was, in Group A (ICL
group) showed UCVA was (0.188±0.123) and UCVA of Group B (Femtosecond assisted LASIK)
was (0.105±0.06) with (p-value <0.133). BCVA of Group one (ICL) was (0.171±0.114) and that
of Group two was (0.105±0.04) with (p-value <0.174). Spherical error in Group A was (0.321±
0,590) and that of Group B (-0.75±0.31) postoperative with (p-value <0.001*). Cylindrical error
was (-0.392±0.318) and Group two was (-0.750±0.204) with (p-value <0.00*). Spherical equivalent in
Group A was (-0.00±0.433) and that of Group B was (-1.12±0.748) with (p-value <0.004*). Contrast
sensitivity of Group A was (132.57±39.99) and that of Group B (102.857±23.688), with (p-value
<0.075). There wasnít significant difference in RMS Group A (0.770±0.21) and that of Group B
(1.15±0.53) with (p-value <0.22). There was significant difference in mean values of spherical
aberrations of Group A (-0.13±0.9123), Group B (0.781±0.406) with (p-value <0.001*) , coma of
Group A (0.131±0.0649), Group B (0.4600±0.2075) with (p-value <0.011*) and trefoil high order
aberrations of Group A (-0.151±0.09), Group B (0.282±0.11) with (p-value <0.03* . Conclusion:
Both implantable collamer lens and femtosecond assisted LASIK proved good visual quality
regarding visual acuity and contrast sensitivity in photopic conditions. For optical quality both
induced high order aberrations which were more in Femtosecond assisted group.