Two filed experiments were carried out at the Experimental Farm, Faculty of Agriculture (Saba Basha), Alexandria University at Abees region, Alexandria, Egypt during the two growing seasons of 2014 and 2015 to study theeffect of mineral, organic and bio-fertilization on growth and productivity of moringa plants (Moringa oleifera, Lam).The experimental design was split plot were three replicates. The main plot were conducted for the five combination of organic manure plus mineral fertilizer of (100% organic, 75% organic manure + 25% mineral, 50% organic manure + 50% mineral, 25% organic manure + 75% mineral and 100% mineral), while, the four bio-fertilization treatments were uninoculation, phosphorein, A- mycorrhizal and cerealine were arranged in the sub-plot. The main results could be summarized as follows: (1) The application of 75% organic manure + 25% mineral; gave the highest mean values of all studied characters, (2) the application of 75% organic manure + 25% mineral with A- mycorrhizal inoculation was the best combination to obtain the highest mean values of plant height, stem length, stem diameter, number of branches /plant, fresh and dry weights/plant, K (%), total carbohydrate (%) and vitamin (C). However, all traits under study increased significantly due to inoculation treatments over the application 100% mineral with uninoculation treatments.