Two field experiments were conducted at North of El Tahrir, El- Behira, Egypt, during 2015 and 2016 seasons, to study the effect of mineral fertilization and organic manure on three maize hybrids. Split plot design with three replications was used, where the main plots contain combination of mineral fertilization (M) + organic manure (OM) i.e., (100 % M,75% M+ 25% OM, 50% M +50% OM, 75% M +25%OM and 100% OM), meanwhile the three maize hybrids (SC.2031, SC.2030 and TWC1100) were allocated in the sub plots. Plot size was 10.50 m² (3 m x 3.5 m) having 5 ridges of 3 m in length and 0.7 m in width. The obtained results revealed that combined application of 75% mineral + 25% organic manure) affected significantly increase in plant height (cm), ear length, number grains/row, number of grains/ear, 100 - grain weight, grain, straw, and biological yield (kg/fed.), and harvest index %. The maize hybrid SC. 2031 recorded the highest means values of above mentioned characters. Fertilizing maize hybrid SC2031 by 75 % mineral + 25% organic manure gave the highest grain yield and its components under this study.