This study was carried out during the two successive seasons of both 2018 and 2019 on 5-year-old Flame Seedless grapevines in a private vineyard located at Kom Hamada - Beheira Governorate, Egypt. The trees were spaced at 1.5 x 3 m apart and irrigated by drip irrigation system and received similar cultural practices adapted in the orchard. The present investigation aimed at study yield and quality of table grapes cv. "Flame seedless" as affected by bud break and pre-harvest treatments. This experiment consisted of sixteen treatments arranged in factorial experiment in Randomized Complete Block Design (RCBD) with four replicates for each treatment and one tree for each replicate. The experiment consisted of 16 treatments (Control, Garlic oil at 1 %, Urea at 2 %, Dormex at 4 %, Abscisic acid at 400 mg/ l, Ethrel at 250 mg/ l, Gibberelic acid 250 mg/ l, Garlic oil at 1 % + ASA at 400 mg/l , Garlic oil at 1 % + Ethrel at 250 mg/l, Garlic oil at 1 % + GA₃ at 250 mg/l, Urea at 2 % + ASA at 400 mg/l, Urea at 2 % + Ethrel at 250 mg/l , Urea at 2 % + GA₃ at 250 mg/l, Dormex at 4 % + ASA at 400 mg/l , Dormex at 4 % + Ethrel at 250 mg/l and Dormex at 4 % + GA₃ at 250 mg/l . Results revealed that spraying dormex at 4%, recorded the best values of cluster weight and yield/plant, physical characters i.e. (berry length, berry diameter, weight of100 berry, size of 100 berry and fruit firmness), and all chemical compositions i.e. (total sugars, reducing sugars, anthocyanin content and vitamin c), also, abscisic acid 400 mg/l gave the highest mean values of cluster weight, yield/plant and anthocyanin content, while Ethrel at 250 mg/l recorded the maximum values of physical characters i.e. (berry length, berry diameter, weight of100 berry, size of 100 berry and fruit firmness), and all chemical compositions i.e. (total sugars, reducing sugars, and vitamin c), as compared with the control treatment which recorded the minimum values of this studied characters, during both seasons.