The study was carried out on cotton variety Giza 86 during two following seasons in 2017 and 2019 at the experimental farms of the faculties of Agriculture, Saba Bacha and El-Chatby, Alexandria, Egypt. The obtained results indicated that the highest efficacy was gained by Novatrin/ Radiant^® and  Novatrin/ Super Mix, which decreased the incidence of Earias insulana (0.84 and 1.24 larvae /10 green bolls, in respect) and pectinophora gossypiella infestation and increased the cotton yield up to (57.8 Kent/  fed(. Furthermore, Novatrin/ Super Mix and Super Mix/Radiant^® - achieved the lowest value of yield losses(9.6% and 10.1%, respectively) during the cotton season of 2017, in addition to the foliar treatments of Novatrin/ Super Mix/Radiant^® and Super Mix/ Potasin-F/ Radiant^® gave higher efficacy in reducing the level of the spiny bollworm infestation(0.53 and 0.65 larvae /10 green bolls, respectively) in 2019 season, while the application of Novatrin/ Super Mix/Radiant^® and Novatrin/Potasin-F/Radiant^®, increased the cotton yield (106.2% and 84.9%, in respect) resulting in decreasing yield losses during the 2019 cotton season, while the foliar application of Novatrin / Super Mix, increased cotton fiber length(34.21mm), while the application of lambda - cyhalothrin and Super Mix greatly increased fiber strength (50.36 and 50.16 gram/ tex, respectively), the highest increased value of fiber micronair reading was detected for the performed application of Super Mix / Radiant^® (4.88 millitex)during the 2017 cotton season, while the application of Novatrin / Potasin-F / Radiant^® increased fiber length (33.66 mm), Novatrin / Super Mix / Radiant^® treatments also increased fiber strength (45.53 gram/ tex) and the value of elongation (5.60%), as well as, application of Novatrin / Potasin-F/ chloropyrifos increased value of fiber micronair reading (4.88 millitex) during the 2019 cotton season.