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163468

Effects of Qat Water Extract Combined with Sublethal Dose of Cypermethrin on Fetuses Body Weight and Length of Pregnant Mice

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Last updated: 05 Jan 2025

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Abstract

The effect of Qat water extract and sublethal concentration of Cypermethrin as active ingredient (A.I.) or formulated type (F) alone or in combination with Qat was evaluated on mice fetuses body weight and length. Female mice were exposed to these treatments during 6th – 18th day of gestation. The results showed that there were  significant reductionin mice fetuses body weight and length due to the administration of Qat extract alone, Cypermethrin  alone, or the combinations of 5g/kg Qat extract with the respective sublethal dose of 1/10 th LD50 (25 mg/kg) of either insecticide type. The formulated Cypermethrin (F) was more effective than its active ingredient type in all experiments, where the tested commercial formulation of Cypermethrin (Cymbush® 10 % E.C.) showed a dramatic significant reduction in the fetuses body weight and length compared with the control. The reduction of body weight and length was higher in case of Qat extract (5g/kg) + 1/10 th LD50 of Cypermethrin formulation treatment with a mean reduction percentage of 40.00% of fetuses body weight and 59.31% of fetuses body length, while the mean reduction percentages for Cypermethrin (A.I.) were 36.24% and 51.91%, respectively. Qat extract alone had a reduction percentage of 15.07% of fetuses body weight. It could be concluded that there is might be high a risk for those pregnant women who comsume Qat.

DOI

10.21608/jalexu.2019.163468

Keywords

Qat (Khat) extract, cypermethrin, Combinations, sublethal dose, fetuses body weight and length of the pregnant mice

Authors

First Name

Hussein

Last Name

Gumaih

MiddleName

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Affiliation

Physiology, Biology Department, Faculty of Science, Sana'a Univ., Yemen

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Orcid

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First Name

Tawfik

Last Name

AL-Busaili

MiddleName

Abdelrab

Affiliation

Obstetrics and Gynecology Department, Faculty of Medicine and Health Sciences, Sana’a University , Obstetrics and Gynecology, Al-Sabain Hospital, Republic of Yemen

Email

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City

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Orcid

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First Name

Mona

Last Name

Al-Kabzari

MiddleName

Ahmed

Affiliation

Agricultural Research and Extension Authority (AREA), Dhamar, Yemen

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Volume

24

Article Issue

3

Related Issue

23653

Issue Date

2019-09-01

Receive Date

2019-07-21

Publish Date

2019-10-01

Page Start

370

Page End

381

Print ISSN

1110-5585

Online ISSN

2785-9525

Link

https://jalexu.journals.ekb.eg/article_163468.html

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https://jalexu.journals.ekb.eg/service?article_code=163468

Order

10

Type

Research papers

Type Code

1,789

Publication Type

Journal

Publication Title

Journal of the Advances in Agricultural Researches

Publication Link

https://jalexu.journals.ekb.eg/

MainTitle

Effects of Qat Water Extract Combined with Sublethal Dose of Cypermethrin on Fetuses Body Weight and Length of Pregnant Mice

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Article

Created At

23 Jan 2023