a feeding study was conducted to evaluate the effect of different natural phytochemicals as alternative sex-reversal agents instead of 17α-methyl testosterone (MT). Newly hatched Nile tilapia (Oreochromis niloticus) fry were treated with MT (60 mg/kg), ginseng extract (GE; 0.2 or 0.4 g/kg), Tribulus terrestris extract (TTE; 0.6 or 1.2 g/kg) and date palm pollen (DPP; 3 or 6 g/kg) in diet. The treatment period lasted for 28 days for MT and 84 days for other phytochemicals. The results showed that the maximum male percentage recorded with MT (92.30%), followed by TTE (1.2 g/kg; 64.48%), TTE (0.6 g/kg; 57.76%) and DPP (6 g/kg; 56.67%), while the male percentage of the control was 48.36%. All studied treatments showed normal survival rates along the experimental period, which proves that the used phytochemicals are nontoxic. Fish treated with phytochemicals exhibited successful growth acceleration compared to the control group especially with TTE treatments. The same manner was observed with feed conversion ratio. Carcass composition showed that MT treatment has significantly increased moisture and decreased ether extract than other treatments. The effects of phytochemicals showed a slight improvement of protein and ether extract content compared to the control diet. Consequently, it can be concluded that the use of phytochemicals in fish diets as growth promoters is more effective than sex-reversal agents. It is recommended to use TTE in Nile tilapia fry diets.