The present study investigated the mechanisms and methods which the October 6 University sophomores prefer for conducting the course of microteaching during the COVID-19 pandemic. It analyzed whether the participants prefer face-to-face lectures or online lectures in studying the microteaching course. The study also discussed the types of online lectures which the participants prefer and accounted for their preference. The study evaluated the participants' views on the methods in which the microteaching lectures can be conducted. Whether the microteaching lectures should separate or combine theory and practice under the circumstances of COVID-19. The study adopted a semi-quasi research design as it surveyed the perception of some sophomore students, at the faculty of Education, October 6 University, about the mechanisms and methods of conducting the practically and theoretically based course of microteaching. Thus, the study adopted a mixed quantitative and qualitative method. Quantification of collected data appears in using descriptive statistics to analyze the participants' responses to the questionnaire and the semi-structured interview based tasks. Meanwhile the analysis of qualitative data is embodied in the description of such responses. The findings indicated that the participants preferred the online lectures to the face-to-face lectures because of the impact of the global COVID-19 crisis. As for online programmes, they signaled out the Microsoft teams programme to have microteaching lecture. As for the methods of conducting the microteaching course, they opted for the theoretically-practically combined sessions. The current study introduced implications for the teaching of microteaching course in the Egyptian context during that pandemic.