Susceptibility of wheat varieties to the infestation with some insect pests. The Rhyzopertha dominica in the non-choice test, Sids1, Beny-sewif-5 and Giza-168 gave the highest weight after damage (49.90g) from the total of 50 g of each variety Sids-1, Beny-sewif-5 and Giza-168 While Sids-12 gave the lowest weight after damage and represented by 48.97g. with significantly differences between different wheat varieties Moreover, the highest percentages weight losses were observed in Sids-12(2.0%) and the least ones were observed in Sids-1, Beny-sewif-5 and Giza-168 represented by 0.20% in one generation After two generations the same trend were observed. In the free choice test, Beny-sewif-5 and Sohag-5 gave the highest weights after damage and represented by 49.90g. in both generations While the Sids-12 gave the lowest weight after damage and represented by 48.50g and 47.60g after one and two generations respectively with significantly differences between different wheat varieties. Sids-12 gave the highest weight loss represented by 2.06 and 5.0% in one and two generations. In non-choice test, the same trend was recorded with Triticum caestivum as previously mentioned with Rhyzopertha dominica and gave the weights of 49.70 and 49.08g in both of two generations. While the Sids-1 gave the highest weight loss and represented by 3.50% and 5.50% after one and two generations with significantly differences between varieties. In free Choice test, the Beny-sewif-5 and Giza-168 gave the highest weights after damage and represented by 49.55 and 49.35g after one and two generations with significantly differences between varieties. Moreover the Sids-1 and Sids-12 gave the highest weight losses and represented by 3.60% and 5.90% after one and two generations with significantly difference between varieties.