This study was carried out to assess the influence of foliar application of multi-micronutrient (250 ppm iron, 200 ppm zinc and 100 ppm boron (and polyamine (spermine) at two concentrations (0.05 and 0.1 mM/Lit) once individually at 7 cm long grown panicles, during full bloom and at initial fruit set stage on alphonse mango trees cvs to enhance leaf micronutrient content, blooming characteristics, fruiting aspects, fruit quality upon harvest during 2017 and 2018 growing seasons. the result showed that The multi-micronutrient treatment at various treatments spraying dates (7cm long grown panicles, full bloom and initial fruit set) with alphonse variety could be consider a useful technology for improving leaf zinc content (mg/100g), fruit set (%), fruit number/tree, fruit yield (Kg/tree), fruit weight (g), fruit peel weight (g) and fruit total soluble solids (%) and reducing fruit drop (%). Also, the spermine treatment at 0.05 and 0.1 mM/Lit. for improving sex expression (%) and fruit TSS/acid ratio.