Purpose: The aim of this study will be the evaluation of the stresses around 2 implants inserted with different degrees of mesial angulations and retained mandibular overdenture with locator attachment using strain gauge analysis. Materials and methods: Four experimental acrylic mandibular edentulous model were constructed. In the canine regions of each model, Two recesses were prepared vertical to the residual ridge (Group I, control), and at 10(Group II), 20(Group III), and 30(Group IV) degree of mesial implant inclination (away from mid line). Two dummy implants were inserted in each model and 1.5-mm-thick layer of autopolymerized resilient silicone soft lining material was used to simulate resilient edentulous ridge mucosa. Four duplicate mandibular record block were constructed and connected to the implants using Locator attachments. Four linear strain gauges were bonded to the acrylic resin at mesial,distal,buccal and lingual surface of each implant to monitor the strain around the implants on loading and non-loading sided during unilateral and bilateral load application. Result: Comparison of microstrains between groups (regardless of sites of measurements, loading side and loading application).There was a significant difference between groups .Multiple comparisons between groups (Bonferroni) 30^o pink recorded the highest microstrain values, followed by 20^o pink, 10^o pink, and 0^o pink recorded the lowest values. Key words: implant overdenture,inclined implant.stress guage.