Objective: The aim of this study was to assess the concentration of ‎hepatocyte growth factor ‎in the gingival ‎crevicular fluid of chronic ‎gingivitis patients.‎ Patients and Methods:‎ A total of twenty patients were selected and grouped as follow; group I included ‎ten ‎chronic gingivitis patients and ‎Group II included ten systemically and ‎clinical ‎periodontal healthy subjects. ‎Hepatocyte growth ‎factor concentration was measured in ‎gingival crevicular ‎fluid samples ‎which ‎‏were collected from the study ‎group and control group. The GCF samples were analyzed ‎using ‎ELISA ‎method to evaluate HGF ‎concentration.   ‎ ‎ ‎ Results: ‎Analysis of hepatocyte growth factor in gingival crevicular ‎fluid at ‎base ‎line showed ‎significantly higher levels in patients of ‎chronic ‎gingivitis ‎ as compared ‎to the controls. Conclusion: Hepatocyte growth factor may be ‎considered as a ‎potential ‎diagnostic ‎biomarker for ‎assessment of ‎periodontal ‎disease activity ‎in ‎GCF.‎