Aim:The aim of the study is to assess the effect of omega-3 fatty acids with nonsurgical periodontal therapy on C-reactive protein level in chronic periodontitis patient.
Subjects and Methods:Thirty participants were involved in this study. Twenty patients with chronic periodontitis were divided equally into study and positive control groups. Ten healthy subjects free from periodontal diseases were enrolled in the study as a negative control group. Clinical periodontal parameters (plaque index, gingival index, bleeding index, periodontal pocket depth and clinical attachment loss) were recorded at baseline for all groups. After 1 and 2 month periodontal indices were recorded again for the study and positive control group only. Serum samples were taken two times (at baseline and 2 months after treatment) from each patient in the study and positive control groups. However, in control group serum sample were taken only once all the beginning. The blood samples were analyzed using CRP serology.
Results:All the clinical periodontal indices and CRP of both the study and positive control were significantly higher than that of negative control group. After treatment theywere significantly reduced.Concerning all chronic periodontitis patient (study & positive control groups). Finally no significant different was found between CRP level of study & positive control groups.
Conclusions:Serum CRP can be used as a biomarker for chronic periodontitis where it has a positive correlation with its severity. Omega-3 has a non-significant effect on reducing the serum level of C-reactive protein if administered as 600 mg/ day for 8 weeks in addition to SRP in chronic periodontitis patients.