Mohamed H. EL Kenawy¹, Una M. El Shinnawi², Ahmed M. Salem³and Fakhrdin H. Ahmed^{4 1} Professor of Oral and Maxillofacial Surgery, Faculty of Dentistry, Mansoura University, Egypt. ² Professor of Oral Medicine and Periodontology, Faculty of Dentistry, Mansoura University, Egypt. ³Assistant Professor of Oral and Maxillofacial Surgery, Faculty of Dentistry, Mansoura University, Egypt. ⁴ Teaching assistant, Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Mansoura University, Egypt. Abstract: Objectives: The aim of this study will be to evaluate the clinical and radiographic efficacy of platelet rich fibrin (PRF) membrane used with immediately placed dental implants in the esthetic zone. Methods: A clinical trial was carried out on fifteen fresh extraction sockets in 7 males and 8 female's patients with age range from 18 to 43 years, sockets implanted with immediate endosseous implant and grafted with deproteinized bovine bone mineral (DBBM) and PRF. After implant placement all implants were evaluated clinically and radiographically at baseline, 3 months, 6 months, 9 months and 12 months. Clinical (modified sulcus bleeding index mSBI, probing pocket depth PPD and degree of mobility using Periotest device) and radiographic parameters (marginal bone loss MBL) were assessed. Results: During the 1-year interval, no implant was lost and all patients showed favorable clinical and radiographic finding. Periotest evaluation showed that all implants were well osseointegrated and stable. There was no statistically significant difference in mSBI (p value 0.055). There was a statistically significant increase in PD and MBL through the whole study period (P value <0.001). Conclusions: Immediate placement of implants with a PRF membranes could be considered a valuable option to replace a missing teeth. Integrating this technique into common practice could provide important benefits for the patients regarding aesthetics, without any risk of infection or transmission of diseases. keywords: Immediate implant, PRF, DBBM, periotest.