Irrigation of the canals is an essentialstage for success of endodontic treatment ,there are many available irrigating solutions and intracanal medications ,however there is no ideal material as most of them shows cytotoxic and side effects ,hence was the search of a more biocompatible new materials and so many herbs were investigated for their advantages in endodontics from these herbs Asiaticoide shows good potential to be used as an irrigating and intracanal medication .