The main objective of root canal treatment is complete debridement  of microorganisms from the infected root canals. Although cleaning and shaping reduce microorganisms, the use of irrigants and medicaments is complimentary to instrumentation in facilitating their removal. Several chemicals and therapeutic agents are used to achieve this goal. However, owing to the potential  side effects, constant increase in antibiotic resistant strains, safety concerns, (1, 2) and cytotoxic reactions of synthetic irrigants and medicaments (3)usage of various herbal agents has increased over the last few decades, (4, 5) and the search is on for a root canal irrigant and medicaments  that can match or better the gold standard.Natural products have been used since ancient times in folk medicine,In dentistry, phytomedicines have been widely used. Herbs with medicinal properties are useful and effective source for treatment of various disease processes. Among them, Oleanolic acid, an example of a pentacyclic triterpenoid originating from a number of medicinal plants, has antimicrobial activity against various bacterial pathogens, and has various bioactivity  (6, 7) .