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Evaluation of salivary immunoglobulin A concentrations in gingivitis and chronic periodontitis patients.

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Last updated: 05 Jan 2025

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Abstract

Background:Salivary immunoglobulin A considers a natural defense mechanism in saliva. It has an important role in preventing bacterial adherence and penetration into the oral mucosal epithelium. It could help preserving the integrity of the oral surfaces. Aim of study:The aim of the study was to assess the correlation between concentration of SIgA and health of periodontal tissues. Subject and methods:Thirty subjects were included in the study. Ten subject as healthy control, ten patients with gingivitis, and ten patients with chronic periodontitis. Full-mouth clinical periodontal parameters were recorded at base line in all groups and after treatment in both study groups. Saliva samples were collected at base line and six weeks after therapy. SIgA level was measured using immunoturbidmetric method and data were statistically analyzed. Result:The result of the present study showed a significant improvement in all clinical parameter (GI, PI, PBI, PPD and CAL) after phase I therapy in gingivitis and chronic periodontitis groups. At the baseline, the salivary IgA levels were significantly higher in gingivitis and chronic periodontitis patient than healthy subjects were. After phase I therapy, there were a significant decrease in SIgA concentrations in gingivitis and chronic periodontitis patients versus there concentrations at the base line.   Conclusion andRecommendations:Scaling and root planning is the mainstay of treatment of periodontal diseases, as it improved clinical parameter in-patient with gingivitis and chronic periodontitis. This study showed increased level of salivary IgA in patients with gingivitis and chronic periodontitis compared with the healthy controlled Additional studies are required to evaluate of salivary immunoglobulin A concentrations in patients with diseased periodontal tissues.  

DOI

10.21608/mjd.2019.199093

Volume

6

Article Issue

1

Related Issue

28096

Issue Date

2019-01-01

Receive Date

2021-10-11

Publish Date

2019-01-01

Page Start

63

Page End

65

Print ISSN

2735-4172

Online ISSN

2812-5479

Link

https://mjd.journals.ekb.eg/article_199093.html

Detail API

https://mjd.journals.ekb.eg/service?article_code=199093

Order

15

Type

Original Article

Type Code

1,715

Publication Type

Journal

Publication Title

Mansoura Journal of Dentistry

Publication Link

https://mjd.journals.ekb.eg/

MainTitle

Evaluation of salivary immunoglobulin A concentrations in gingivitis and chronic periodontitis patients.

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Type

Article

Created At

23 Jan 2023