Abstract. - Present study is a part of the project conducted by National Nutrition Institute to evaluate the pollution effect on the health of occupationally exposed workers in some industries in Egypt. The various blood and urine biochemical parameters of a total included 1816 workers select randomly from seven Textile factories distributed in five governorates, were compared to assess the gender, job duration time and workplace. The results indicated that the biochemical analysis of antioxidants (Glutathione (GSH), Malondialdehyde (MDA) and erythrocyte super oxide dismutase (cu/znSOD)), the mean values ofGSH and cu/znSOD were significantly higher in males, while the mean value of MDA was not effected by gender. Concerning to job duration the data showed that the mean value of cu/znSOD in indirect group of categories II was significantly increase than of the corresponding group in category I.The mean value of MDA level of indirect & direct groups in category I were significantly increase than the corresponding groups of categories II. On the other hand, the mean value GSH level was not affected by job duration. According to work place, there was significant increase in GSH mean value of direct workers than of indirect workers in category II. While, the mean value of cu/znSOD in direct workers of category I had significant increase than in indirect of the same category. While MDA mean value was not affected by work place. At the total group level, the mean value in both of GSH &MDA in category II were significantly increase than of the total group in category I.  The present study showed that results of some biochemical parameters as indicators for liver functions, the changes observed in the blood component some correlate with the age, job duration and gender. While other effecting by job duration only. On the other hand, concerning of work place significant change in AlkalinePhosphates (ALP)and value of plasma albumin. The results of some biochemical parameters as indicators for kidney functions were change by gender, job duration and work place.
Key words: Textile workers, Liver functions, Kidney functions, antioxidants and lipid peroxidation.