Background: Body weight, dietary fiber and fat intake are factors that influence serum level of Highly Sensitive C-Reactive protein (CRP) which is a predictor for future cardiovascular diseases.
 
Objectives: To describe the dietary pattern of fiber and fat intake among medical students and to assess the relation between body weight, dietary fiber and fat intake and the hs-CRP level.
 
Methods: A Cross Sectional study was carried out among a sample of medical students at Ain Shams University. A total of 400 medical students were involved, all participants were subjected to self-administered questionnaires including socio demographic, clinical data and 24 hours food recall and food frequency questionnaire. Anthropometric measurement was done in addition to measurement of serum level of hs-CRP. Calculation of nutritional intake of fibers and fat was further analyzed using software Foods System V2 Nutri Plus, which is based on Composition of Foods.
 
Results: the mean age was (21.4 +1.99), 79% were females. Adequate fiber in diet was consumed by (26.75%) of students, and 39.75% exceeded the recommended fat intake. Hs-CRP level was positively correlated with body weight, visceral fat and dietary fat intake and negatively correlated with dietary fiber intake. Multiple linear regression showed that female gender, body mass index, waist hip ratio, visceral fat and fiber in diet were significantly associated with hs-CRP level.
 
Conclusion: Increasing fiber and decrease fat intake are protective factors against increasing hs-CRP level.
Key words: CRP- fiber-body weight-students