This study was undertaken to determine the effects of regimen diet with or without containing yogurt supplemented with lemon or cumin and mixture of  them on body weight reduction, fasting blood glucose and  glucated hemoglobin HbA_1c levels. A random sample of 100 patients (50 male and 50 female) with obesity or overweight, were selected from Kasr El-Aini Hospital out patients, with age from 30-45 years.  Randomly patients were devided into 5 groups, each group includs 20 patients 10 male and 10 female.  Body weight and blood samples were collected from all participants at baseline and after 12 weeks to determine BMI, the fasting blood glucose and Hb A_1c.  The first group kept on their usual diet and considered as control (+ve) group. 
The second group treated only with regimen diet depend on BMI (1200 K.Cal(60gm protein ,40gm fat &150 carbohydrate) or 1500 K.Cal (75 gm protein,50gm fat & 187.5 carbohydrate)for overweight or obese patients) the third group treated with the same (RD) plus a dose of cumin in amount of 5g/d for 12 weeks.  The fourth group received (RD) plus a dose of lemon 5g/ d.  The fifth group received (RD) containing a dose of cumin 2.5g/d mixed with 2.5 g lemon/d  (1:1w/w).
 
After 12 weeks of regimen dietary treatments, Results revealed that regimen diet (1200 or 1500 K.Cal/d) containing skim milk yogurt supplemented with cumin, lemon and mixture of them (1:1w/w) induced a high significant decrease in BMI, Fasting blood glucos and glycated hemoglobin HbA­_1c levels as compared to at baseline and as compared to control which treated with only regimen diet.  In conclusion, or results showed that regimen diet containing skim milk yogurt supplemented with a mixed of cumin plus lemon (1:1w/w) induced a high significant (P<0.01) decrease in BMI, fasting blood glucose and glycated hemoglobin in obese and over weight patients.  Therefore mixed cumin and lemon (1:1w/w) may  represent a potentially therapeutic effect on decreasing BMI in obese and overweight patients.