Egyptian J. of Nutrition Vol. XXXIII No.3 (2018) Nutritional And Biochemical Effects OfGum Arabic On The Pathological Changes Reduction OfAlloxan Induced Diabetic Rats EnsafM. Yassin Nutrition and Food Science Dept, Faculty ofHome Economics, AI­Azhar University, Egypt Abstract Natural substances have been used as a source of medicinal treatments for several decades and plants-based products playa critical role in the treatment of diabetes mellitus (DM) globally. This study was conducted to acquaintancethe effectiveness of gum Arabic (GA)on experimental rats suffered from diabetes mellitus.Thirty six mature male albino rats "Sprague Dawley" strain weighing (160±10 g), were used and divided into two main groups, one was kept as a negative control group (n =6) (G1), while the other was injected infra peritoneally with alloxan monohydrate by a single"'alose of alloxan (1S0mg/kg/B.W.) in 24 hrs fasting animal. This second main group divided into equal five groups (n =6);. The five diabetic groups were as the following; Group (2): was left as positive control and fed on basal diet only. Group (3): was fed on basal diet supplemented with diamacron drl1g1Smg Ikg diet.Group (4): was fed on basal diet supplemented with SO g GA (S%) Ikg diet. Group (5): was fed on basal diet supplemented with 100 g GA (10%)1 kg diet. Group (6): was fed