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143376

Therapeutic Effect of Dried Fig, Date and Olive Oil on Immune System in Rats

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Last updated: 23 Jan 2023

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Abstract

 The aim of the present work was to investigate the effect of dried fig, date and olive oil supplementation on hematological parameters and immune functions in rats.Fifty four male albino rats weighing 120 ± 5 g were used in this study. The first main group (n=6) was fed on the basal diet(-ve control).The second main group (n = 48) was subcutaneously injected with a single dose ofSheep red blood cell (SRBC) to induced immune suppuration. Then rats weredivided into 8 subgroups (6 rats each).Subgroup 1was fed on basal diet (+ve control).Subgroups from 2 - 4 were fed on the basal diet and supplemented with olive oil 5% , dried fig 10%,and date 10%, separately.Subgroups from 5 - 7 were fed onbasal diets supplemented with olive oil 5%, dried fig10%, and date 10% respectively.Subgroup 8 was fed onbasal diet and supplemented with a mixture of olive oil 5%, dried fig 10%, and date 10%for 8 weeks. Chemical composition results of dried fig, date fruit and olive oil recorded high content of vitamins, minerals, calories and carbohydrates.Olive oil show high content of calories, fats,omega-6 and vitamins but low iron. Dried fig, date and olive oil revealed the presence oftotal phenolic and flavonoid. Results indicated that rats groups fed on a mixture of the three tested samples had increased immune suppurationsignificantly (P<0.05).  The mean value of IgMand IgGare81.4 and749.0 g/L, respectively for the rats fed on mixture of the tested materials increased,compared to the positive control group. Hematological parameters were significantly increased (P<0.05) for the groups given dried fig, olive oil and date fruit separately or in combination. However, white blood cells count was significantly decreased. Moreover, significantincrease inbody weight gain, feed intake and feed efficiency ratio of the tested groups compared to the positive control group. Also, results show significant increase in the levels of white blood cells and hemoglobin compared to the negative control group. It could be concluded that, dried figs, dates fruit and olive oil stimulates the immune system of rats with induced immune deficiency.
                                     

DOI

10.21608/enj.2018.143376

Keywords

Therapeutic Effect of Dried Fig, Date and Olive Oil on Immune System in Rats

Authors

First Name

Hoda S.

Last Name

Ibrahima

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Affiliation

Nutrition and Food Science Department, Faculty of Home Economics, Helwan University.

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First Name

Naeem M.

Last Name

Rabeha

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Affiliation

Nutrition and Food Science Department, Faculty of Home Economics, Helwan University.

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First Name

Hanan M.

Last Name

El-Ghandour

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Affiliation

Regional Center for Food and Feed, Agricultural Research Center.

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First Name

Shafika M.

Last Name

Sabrya

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Affiliation

Nutrition and Food Science Department, Faculty of Home Economics, Helwan University.

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Volume

33

Article Issue

2

Related Issue

21063

Issue Date

2018-06-01

Receive Date

2018-04-16

Publish Date

2018-06-01

Page Start

137

Page End

172

Print ISSN

1687-1235

Online ISSN

2090-2514

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https://ejn.journals.ekb.eg/article_143376.html

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https://ejn.journals.ekb.eg/service?article_code=143376

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4

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Original Article

Type Code

1,704

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Publication Title

Egyptian Journal of Nutrition

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https://ejn.journals.ekb.eg/

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Article

Created At

23 Jan 2023