The aim of this work is to investigate the ability of ingestion two different doses (1ml and 2ml/kg/BW) of fresh red beetroot juice to improve anemia and its effect on final body weight of obese anemic rats. Forty two adult male Sprague- Dawley rats were fed on standard diet for one week for adaptation. Rats were then randomly divided into seven groups (6rats each) as follow: the first group was fed on basal diet only and served as control negative group, while groups (2:4) of rats (n=18) were fed on high fat diet for four weeks to induce obesity, then continuously fed on high fat diet, deficient in iron and supplemented with (10 g tannic acid/kg diet) for further 3 weeks to induce anemia. These rats were then divided into three groups, positive control group and two other groups given orally 1 ml and 2 ml juice /kg BW respectively. Groups (5:7) of rats (n=18) were fed on basal diet, deficient in iron and supplemented with (10 g tannic acid/kg diet) for 3 weeks to induce anemia, then were divided into three groups, one positive control group (anemic) and two other groups given orally 1 ml and 2 ml/kg BW fresh juice red beetroot respectively. The results showed that oral ingestion fresh beetroot juice (1ml and 2 ml/kg.BW) significantly (P <0.05) decreased the final body weight and body weight gain of anemic obese rats, and the weight reduction was 30.25, 39.00 %  respectively due to ingestion fresh red beet juice  that rich in (iron 15.34 mg/100 ml juice). Fresh beetroot juice supplementation decreased significantly (P<0.05) leptin concentrations, Moreover, hemoglobin, hematocrit and red blood cell concentration as well lipid profile and liver function were improved significantly compared to positive control group. The study recommends that obese patients suffering from anemia should drink fresh red beetroot juice.