The study aimed at identifying the concept of cloud computing and explaining the benefits of using cloud computing in the educational process and understanding the impact of the application of cloud computing on the quality of e-learning in developing mathematical knowledge and skills among university students, the study used the semi-experimental approach, and the study sample consisted of a group of female students of the year Preparatory at the University of Tabuk during the academic year 1438/1439 AH, and the results of the study indicated the effectiveness of cloud computing in developing mathematical achievement and developing skills related to mathematics for university students, and the study provided a set of recommendations Research and proposals to increase the use of cloud computing at the University of Tabuk.