The first genetically modified plant has been originated in 1984, since then over 60 species has been found. From the meat industry's point of view the most significant one is the Soybean, where it is used in a wide scale as protein substitute or stabilizers. Moreover it may be used in the processing of meat analogs. In the present study, polymerase chain reaction (PCR) was used to detect native and genetically modified (GM) Soybean in unlabeled meat products (minced meat, beef burger, kofta, and sausage) which commercially sold in Ismailia governorate .The Results revealed that native Soybean was detected at the rate of 60%, 80%, and 90% in the minced meat, beef burger, and sausage samples respectively but not detected in kofta. Whereas GM Soybean detected at rate of 10% in minced meat samples. Consequently public awareness should be performed to establish a systematic food screening method to discriminate between native and genetically modified Soybean in meat products to safeguard the consumers.