Background: Postural scoliosis is one of the most common problems in musculoskeletal system. Cervical proprioception function may be attributed in postural scoliosis. Objective: Determine the relation between postural scoliosis and cervical proprioception function. Subjects, Materials and Methods: Sixty subjects from both sexes represented the sample of the study. Their age ranges from 20-30 years old. Subjects were assigned into two equal groups. Group (I) thirty patients diagnosed with postural scoliosis based on x-ray in addition to thirty normal matched subject's group (II). Cervical range of motion device was used for assessment of proprioception error in all directions. Results: There was a significant (p < 0.05) positive correlation between postural scoliosis and absolute angular error from neutral head posture and target head position in all directions (flexion, extension, right side bending, left side bending, right rotation and left rotation) directions. Conclusion: Postural scoliosis is associated with reduced cervical proprioception function.