Purpose: Study effectiveness of Trypan blue for enhancing visualization during phacoemulsification in cases of cataract with corneal opacities.
Method: a prospective cohort study was conducted on 50 eyes with cataract associated with mild or moderate corneal opacity who were attached to Mansoura ophthalmic center on the period from September 2019 to September 2020 divided into 2 groups (group A; with trypan blue and group B; without trypan blue) followed by assessment of completion of rhexis, endothelial cell density and coefficient of variation using specular microscopy.
Results: Fifty eyes were included in the study, 18 males (36%) and 32 females (64%). There was statistically significant reduction in mean endothelial cell density (cells/mm) in eyes with trypan blue compared to eyes without trypan blue (1329.08±896.53 vs 1865.52±738.37 respectively with p value = 0.025). With no statistically significant difference in coefficient variation.
Conclusion: trypan blue is better in visualization during fashioning capsulorhexis, but has significant effect on endothelial cell density during phacoemulsification with coexistence of corneal opacity.