Multiple cases of cardiovascular involvement, including acute coronary syndrome, have been recorded since the catastrophic epidemic of coronavirus disease 2019 (COVID-19) in early 2020. The purpose of this investigation was to categorise people with acute coronary syndrome (ACS) into one of nineteen different groups. Patients and Methods: From May 2021 to April 2022, 200 patients with ACS were hospitalised to the CCU Department at Benha University Hospital for this prospective research. The GRACE scores of the groups investigated do not vary substantially from one another (non-significantly higher in patients with COVID-19) The results of this research show that people with ACS who also have COVID-19 are more likely to appear late and to die while hospitalised than those with ACS who do not have COVID-19.