Background In late December 2019, a previous unidentified coronavirus, emerged from Wuhan, the disease is officially named as Coronavirus Disease-2019 (COVID-19, by WHO on February 11, 2020) which led to its declaration as a global pandemic, on 11 March 2020 by the World Health Organization, This study aimed to evaluate some ICU severity scoring systems to predict prognosis, mortality rate and survival rate in critically ill patient with COVID 19 infection.  Results: The study was conducted on 100  critically ill patients divided into 2 groups: non survivors group (45 patients), and survivors group (55 patients) showing that the SOFA, qSOFA, APACHE II, MURRAY, 4C mortality and VACO index scores were statistically significant higher in non survivors group. Conclusion: SOFA, qSOFA, APACHE II, MURRAY, 4C Mortality scores and VACO index were statistically significant higher in non survivors groups and significantly can predict mortality in ICU