One of the most popular treatments to address joint pain in individuals with advanced osteoarthritis or rheumatoid arthritis of the knee is total knee arthroplasty (TKA). TKA, on the other hand, is followed by moderate to severe postoperative pain, which has a negative impact on postoperative rehabilitation, patient satisfaction, and the overall results of the procedure. Multimodal analgesia regimens including the Adductor Canal Block (ACB), Infiltration between the Popliteal Artery and the Capsule of the Knee (IPACK) block, and a combination of these are routinely utilised to provide safe early ambulation and rehabilitative activity. The purpose of this research was to assess and evaluate postoperative analgesia following total knee arthroplasty between a combination low volume + Ipack block and a large volume adductor canal block. A prospective, randomised, blind, and matched-pairs clinical trial was used for this study. The institutional ethics committee at Benha University Hospital gave its assent to the study's protocol. There were two groups of sixty patients each. Ultrasound-guided ACB with 20 mL of 0.125 bupivacaine was given to Group I:- Those in this group got the procedure. For Group II, the ACB was performed utilising ultrasound guidance, along with 10 mL of 0.125 bupivacaine and one pack block. Results: The low volume adductor canal block with IPACK block had a lower VAS score and lower opoid intake in the first 24 hours than the large volume adductor canal block, according to this research. In the end, we propose the low volume ACB with IPACK block for postoperative pain after total knee arthroplasty