One of the most common dermatological diseases is acne. Acne scars and pigmentation may have a dramatic psychological effect on people who suffer from severe breakouts. Laser, radiofrequency, chemical, surgical, microneedling, fillers, and/or fat injections are all current therapeutic methods. With less reported downtime than lasers or chemical peels, fractional radiofrequency-based treatments have lately been utilised to reduce acne scars with less risk of scarring or hyperpigmentation. Fractional Co2 Laser therapy of acne scars is the focus of this study. There were 15 individuals with post-acne scars who participated in this research. Fractional Co2 Laser was used on the right side of the patients. They had three monthly sessions of treatment. The sessions were completed in all instances. The mean pain score for the first session of fractional CO2 laser treatment was 60. Within two sessions, it dropped to 57.3 and then to 52.7, indicating a substantial reduction in discomfort with time (p=0.039). Mean improvement scores increased significantly over time (p0.001), according to the findings of this investigation. It was shown that there was a significant difference in the improvement grades across sessions when the improvement score was stratified into grades of moderate and outstanding. Erythema (100 percent) and edoema (20 percent) were the most common side effects of fractional CO2 laser treatment. There aren't any hyperpigmentation or scars to be seen here. Conclusion: Fractional Co2 improved the patient's score greatly, but it was also related with more severe pain and more erythema than usual.