Background: When CKD and CAD are present, they are termed a high-risk combination. Few studies particularly focus on CAD in CKD patients despite the high incidence, and it is often an exclusion factor in most trials. Study's goal was to see whether individuals with CCS who had CKD were more likely to have successful revascularization and have severe adverse cardiovascular events in the future. Aim of The work: This study aims to examine the effect of chronic kidney disease on revascularization and MACE in individuals with CCS. Patients and methods: from November 2019 to October of 2021, Benha University Hospitals and Al Ahrar Teaching Hospital will participate in an observational prospective cross-sectional multicenter research of patients with CCS. Patients with CCS who had PCI revascularization were included in the research. Affected individuals are those with an eGFR less than 60 mL/min/1.73m2. Results: a very high rate of incomplete revascularization (P0.001) was seen in this study. There was a statistically significant difference in the prevalence of MACE (P=0.037). Conclusion: individuals with chronic coronary syndrome are more likely to have an incomplete revascularization if they also have chronic renal disease. MACE is also related with inadequate revascularization.