Nosocomial infections are those that occur in a healthcare facility or hospital environment and are known as hospital-acquired
infections (HAIs). Pseudomonas aeruginosa, E. coli, Klebsiella pneumonia, Enterococci spp, Methicillin-resistant Staphylococcus
aureus (MRSA), and many other bacteria are the primary causes of HAI. Resistance in bacteria can be overcome only by the
intelligent and practical deployment of nanotechnology. Antibacterial resistance has cleared the path for more effective and
sensitive ways for detecting and treating bacterial infections because to Nanotechnology. These nano-composites have been
utilised with molecular beacons to determine bactericidal actions, target medication delivery, and anti-fouling coatings, among
other purposes. More recent approaches to improving efficacy against MDR bacteria, such as combining more than one
nanoparticle with polymer (Nano-composites), have also been summarised. Nano-composite may be used to fight multidrugresistant
bacteria in a novel way, according to our findings.