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199032

Study of Adiponectin Promotor Methylation status in patients with Non Alcoholic Fatty Liver Disease

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Last updated: 28 Dec 2024

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Abstract

Nonalcoholic fatty liver disease (NAFLD) is one of the most common causes of liver disease globally, and it is likely to overtake alcoholic liver disease as the primary cause of end-stage liver disease in the coming decades. It affects both adults and children. In light of the significant hurdles in the prevention and control of NAFLD, recent research have shown that detecting adiponectin promotor methylation may be useful in NAFLD diagnosis, prognosis, and treatment.. Adiponectin (an adipose tissue hormone) induces apoptosis in hepatocytes, which has an anti-steatotic effect. Several samples from patients with NAFLD have been shown to exhibit adiponectin promotor methylation (NAFLD) so it can be used as non- invasive tool for NAFLD diagnosis.

DOI

10.21608/bjas.2021.199032

Keywords

Non alcoholic fatty liver disease, adiponectin, methylation

Authors

First Name

M.A.

Last Name

Abd El-moaty

MiddleName

-

Affiliation

Medical Biochemistry,Molecular Biology,Dept.,Faculty of Medicine, Benha Univ., Benha, Egypt

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City

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Orcid

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First Name

I.A.

Last Name

Elsayed

MiddleName

-

Affiliation

Medical Biochemistry,Molecular Biology,Dept.,Faculty of Medicine, Benha Univ., Benha, Egypt

Email

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City

-

Orcid

-

First Name

Y.

Last Name

Saad

MiddleName

-

Affiliation

Endemic Medicine , hepatogastroenterology, Dept., Faculty of Medicine, cairoUniv., cairo, Egypt

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-

Orcid

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First Name

S.K.

Last Name

Eliwa

MiddleName

-

Affiliation

Medical Biochemistry,Molecular Biology,Dept.,Faculty of Medicine, Benha Univ., Benha, Egypt

Email

-

City

-

Orcid

-

First Name

N.E.

Last Name

Abd El-Maksoud

MiddleName

-

Affiliation

Medical Biochemistry,Molecular Biology,Dept.,Faculty of Medicine, Benha Univ., Benha, Egypt

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Orcid

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Volume

6

Article Issue

5

Related Issue

27998

Issue Date

2021-09-01

Receive Date

2021-10-11

Publish Date

2021-09-01

Page Start

105

Page End

107

Print ISSN

2356-9751

Online ISSN

2356-976X

Article File

BJAS_Volume 6_Issue 5_Pages 105-107.pdf

PDF . 352.5kB

Link

https://bjas.journals.ekb.eg/article_199032.html

Detail API

https://bjas.journals.ekb.eg/service?article_code=199032

Order

17

Type

Original Research Papers

Type Code

1,647

Publication Type

Journal

Publication Title

Benha Journal of Applied Sciences

Publication Link

https://bjas.journals.ekb.eg/

MainTitle

Study of Adiponectin Promotor Methylation status in patients with Non Alcoholic Fatty Liver Disease

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Article

Created At

23 Jan 2023