Background: The diagnostic bronchioscopic interventions primary objective is to evaluate and sample tissue of endobronchial lesions, bronchial, pulmonary, hilar-mediastinal lesions or parenchymal lesions utilising various tools that may be introduced through the FB working channel. Target of the work: Our research is aimed at comparing the effectiveness and diagnostic performance of endobronchial cryobiopsies with forceps biopsies in lung cancer detection. Methods and patients: A total of 60 patients have been enrolled. These individuals have been diagnosed with bronchoscopy owing to suspected lung cancer in order to get final diagnosis tissue samples. All operations were performed utilising local lidocaine 2 percent instillation and Midazolam under IV sedation, without endotracheal intubation. Results: This group comprised a total of 60 individuals with suspected endobronchial lesions. Population figures: 16 female (26.7%) and 44 male (73.3%) with an average age of 63.40 ± 9.77. (16) non-smokers (36) and (8) ex-smokers were found. All procedures were performed under IV Midazolam and local anaesthetic instillation. The diagnostic results of the cryobiopsy samples were significantly larger than those of forceps (p value: 0.005). The ultimate diagnosis of forceps biopsy was found in 60 individuals (100%) compared to 46 (76.7%) with cryobiopsy. Small cell carcinoma was the most frequent diagnosis. Conclusion: Cryobiopsy is a safe and efficient technique for obtaining large tissue samples with better diagnostic efficiency than conventional forceps biopsy.