Background: Meconium drawing is a life-threatening disorder. It is distinguished by significant respiratory difficulties. Lactate is a fast-paced variable, strongly related to difficulties and mortality in nearly every severely sick child. Our aim in this study was to anticipate difficulties with the drawing of meconium by lactate measurement. Methods: This is randomised control work, occurring in 40 babies with meconium stained liquid. From February 2020 until November 2020, they were allowed to attend Benha University Hospital. Results: The need for resuscitation of babies with meconium contaminated liquor was 60 percent. Administration of surfactants was 16 percent. Stay in the hospital, vary from (4-45) days. Diabetic mother's maternal history was 20% and hypertension maternity was 12%. Infant issues report that 20% air leak syndrome, 16% air leak syndrome, 52% hypoxic ischemic encephalopathy and 64% required for breathing assistance. Air leak syndrome Conclusion: Lactate measurement may be utilised to prevent issues such air leak syndrome, ischemic encephalopathy and breathing assistance in babies receiving meconium-treated liquor.