Background: Ankle arthritis is a highly frequent condition and treatment choice in young individuals may be a difficulty. Fifty percent of older people get some sort of foot or ankle arthrosis. The most prevalent cause is post-traumatic arthritis, comprising 70 percent of people with osteoarthritis. Ankle fusion gives a solid foot that is painless, plantigrade. Several various procedures for ankle fusion were documented, although, including external fixators, internal binding and intramedullary nailing, this is a rescue treatment that leads to lasting abnormalities in gait and there is a danger of worsening owing to the danger of developing ipsilateral hind foot arthritis. There are several operational procedures including open or arthroscopic methods for ankle arthrodesis. Following both techniques, successful clinical outcomes may be attained. The major purpose of this research was to assess the clinical impact of arthrodesis of the knee with transfibular fastening. Methods: Methods: This is a study of 20 patients operated on a transfibular basis at university hospitals Benha and El helal. Results and findings: Compared to the pre-operative values, the post-operative AOFAS rear foot score has been significantly improved. In 20 patients, 95% bone union was accomplished which demonstrates that ankle arthrodesis with transfibular fixation results in good clinical results. This method guarantees high bone union rate and strong stability, removes ankle discomfort, corrects deformation and enhances the ankle function substantially.