Presentation: Polycystic Ovary Syndrome is quite possibly the most well-known reasons for anovulatory fruitlessness, influencing 8-13% of conceptive matured ladies . It is by a long shot the most well-known reason for hyperandrogenic anovulatory fruitlessness and was depicted the greater part a century prior, the basic reason for this issue is as yet dubious . Point: to examine the viability of short(2.5mg day by day for 5 days) versus broadened course (2.5mg day by day for 10 days) of letrozole treatment for ovulation acceptance in ladies with polycystic ovary syndrome.Subject &Method: This examination directed on (40) patients with PCOS They were arbitrarily assigned in two gatherings. Gathering 1 (20 patients )got letrozole in adose of 5mg for 5 days while the gathering 2 (20 patients) got letrozole in adose of 2.5 mg for 10 days.Result : The all out number of follicles in the present moment letrozole was 3±1 while it was 4±1 in the long letrozole bunch. In our examination the endometrial thickness was 8±2 in both short and long letrozole bunch .The pregnancy rate was 15% in short letrozole bunch while it was 25% in long letrozole bunch . End: The long letrozole treatment (2.5mg for 10 days) can create more develop follicles and in this manner a greater number of pregnancies than the short letrozole treatment (5mg for 5 days).